Geriatric Physiology and Pharmacology The appropriate pain management regimen starts with a clear understanding of the physiological changes associated with aging and their effect on pharmacology.
There are important barriers to overcome with regard to safe and effective treatment of pain such as proper assessment, multiple comorbid conditions, altered physiology and polypharmacy.
Reduced hepatic metabolism can lead to prolonged drug half-life, thus increasing retention in the blood stream. Effectiveness of direct vs indirect technique of myofascial release in the management of tension-type headache.
Opioid analgesics should be used for pain nonresponsive to nonopioid agents. In the absence of high levels of evidence on which to base treatment, the place of clinical judgment assumes greater importance. The essential focus of medicine is the patient's well-being.
Selective serotonin reuptake inhibitors and the newer serotonin-norepinephrine reuptake inhibitors both inhibit the cytochrome system and can lead to a buildup of other drugs. Pain may be described in terms of intensity, affect, location, or several other domains Ferrell, Introduction Appropriate management of chronic and acute pain in the geriatric population creates several unique challenges, as it is an increasingly common and often undertreated condition.
Acupuncture: In Depth. Standard approaches to the management of postherpetic neuralgia had either been poorly tolerated or ineffective [17,18].